Chronic Pain: Poorly Understood

Chronic Pain Could Have a Unique Genetic Basis in Women

You might think this article is going to tell us that women are more likely than men to suffer from chronic pain, or to be underdiagnosed for it.

It’s not.

My main takeaway is that the causes and manifestations of chronic pain are super duper complex, tied up with immune and psychiactric stuff, and (this is the only new bit of information) on a genetic level they appear to operate very differently between the sexes.

We already know, based on our experience living in the world, that women in general are more likely to get sick than men in general. We know that female athletes are more likely to suffer injuries. But this doesn’t mean that men don’t get sick or injured, just that the circumstances are usually different.

We know that different people experience pain very differently and that pain can be made worse by a variety of factors, including being clinically depressed; being hormonal or pregnant (trust me, it’s true); having red hair (sorry, Dutch and Irish ancestors!); or suffering the effects of diseases such as dengue, malaria, fibromyalgia, or Lyme disease. We know that amputees can experience pain in their missing limb, which seems really unfair, and that pain can take on a life of its own and linger in a person’s system long after the initial cause has passed.

The bottom line is, I think we all would like a world where no one experiences chronic pain. Failing that, we’d like to help sufferers as much as possible, above all by believing them. This article nudges us a little closer to that, mostly by confirming: Yep, it really is really really complicated.

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